The pharmaceutical industry and mainly Custom Manufacturing Organization’s need a tool to be able to produce API’s and intermediates. These may require hydrogenation and/or other gas/liquid reactions, including catalyst-filtration, distillation, condensation and cover a wide range of conditions of the daily business in Pharma such as:
Additionally, the unit has to be available quickly and provide a cost-effective investment.
With these objectives in mind, BIAZZI answered the call to develop a high end, multipurpose standardized offering, while also providing various options for customization. The Biazzi BSPS is an optimal production tool, easy to implement, effective, and available for a minimal capital investment.
BIAZZI is offering the following multipurpose batch wise operated gas-liquid plant, supplied as skid mounted unit. The plant enables to perform hydrogenation, oxidation, carbonylation and amination reactions. Beside Gas-Liquid-reactions and/or Liquid-Liquid-reactions can be run.
These process equipment and main process can be schematized as follows:
Operating conditions and properties of the BSPS:
Active pharmaceutical ingredients and/or intermediates in aqueous solution or in solvents.
Most common solvents that can be used are:
Alcohols
Isopropanol
Isobutanol
Ethanol
Methanol
Etc.
Ethers
Methyl-THF
Dioxane
Ethyl ether
Tetrahydrofuran
Etc.
Ketones
Acetone
Methyl Ethyl Ketone (MEK)
Etc.
Esters
Ethyl acetate
Etc.
Halogen based solvents
Ethylene bromide
Dichloromethane
Tetrachloroethylene
Diluted acids
Hydrochloric acid
Acetic Acid
Etc.
Aliphatic
Cyclohexane
Hexane
Etc.
Aromatics
Toluene
Xylene
Etc.
Alkaline diluted compounds
Sodium- / Potassium-Hydroxide
Ammonia-Solution
Typical heterogeneous catalysts used for gas-liquid reactions:
Scope of supply of the BSPS-BASIS-MODEL
BSPS-Basis model. Dimensions: 2.2m (L) x 2.2m (W) x 3.2m (H)
Options available for the BSPS
BSPS-All options model. Dimensions: 3.1m (L) x 2.2m (W) x 3.2m (H)
Please contact us:
or contact us by phone:
+41 21 989 21 21